Article
Characterization and differential expression of cathepsin L3 alleles from Fasciola hepatica.
Molecular and biochemical parasitology - 1 Jul 2013
Zawistowska-Deniziak A, Wasyl K, Norbury L J, Wesołowska A, Bień J, Grodzik M, Wiśniewski M, Bąska P, Wędrychowicz H
Abstract excerpt
Fasciola hepatica infections cause significant global problems in veterinary and human medicine, including causing huge losses in cattle and sheep production. F. hepatica host infection is a multistage process and flukes express papain-like cysteine proteases, termed cathepsins, which play pivotal roles in virulence through host entry, tissue migration and immune evasion. Expression of these proteases is...
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