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Article

The evolution of enzyme specificity in Fasciola spp.

Journal of molecular evolution - 1 Jul 2003

Irving James A, Spithill Terry W, Pike Robert N, Whisstock James C, Smooker Peter M

Abstract excerpt

Fasciola spp., commonly known as liver fluke, are significant trematode parasites of livestock and humans. They secrete several cathepsin L-like cysteine proteases, some of which differ in enzymatic properties and timing of expression in the parasite's life cycle. A detailed sequence and evolutionary analysis is presented, based on 18 cathepsin L-like enzymes isolated from Fasciola spp. (including a novel clone...

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Source

Identifiers

PMID: 12962301
DOI: 10.1007/s00239-002-2434-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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