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Article

TPO genetic variants and risk of differentiated thyroid carcinoma in two European populations.

International journal of cancer - 15 Dec 2013

Cipollini Monica, Pastor Susana, Gemignani Federica, Castell Juan, Garritano Sonia, Bonotti Alessandra, Biarnés Josefina, Figlioli Gisella, Romei Cristina, Marcos Ricard, Cristaudo Alfonso, Elisei Rossella, Landi Stefano, Velázquez Antonia

Abstract excerpt

Thyroid cancer risk involves the interaction of genetic and environmental factors. The thyroperoxidase (TPO) has a key role in the iodine metabolism, being essential for the thyroid function. Mutations in the TPO gene are common in congenital hypothyroidism, and there are also signs of the implication of TPO in thyroid cancer. We performed a case-control association study of genetic variants in TPO and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23754668
DOI: 10.1002/ijc.28317

Genes

TPO

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