Article
Genetic analysis of attachment glycoprotein (G) gene in new genotype ON1 of human respiratory syncytial virus detected in Japan.
Microbiology and immunology - 1 Sept 2013
Tsukagoshi Hiroyuki, Yokoi Hajime, Kobayashi Miho, Kushibuchi Izumi, Okamoto-Nakagawa Reiko, Yoshida Ayako, Morita Yukio, Noda Masahiro, Yamamoto Norio, Sugai Kazuko, Oishi Kazunori, Kozawa Kunihisa, Kuroda Makoto, Shirabe Komei, Kimura Hirokazu
Abstract excerpt
We studied the evolution of the G gene in the new genotype ON1 of RSV detected from patients with acute respiratory infection in Japan. Phylogenetic analyses and the evolutionary timescale were obtained by the Bayesian MCMC method. We also analyzed p-distance and positive selection sites. A new genotype ON1 emerged around 2001. The evolution rate was rapid (3.57 × 10(-3) substitutions/site per year). The...
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