Article
[Gene sequence and antigenic epitope variation within the F protein of respiratory syncytial virus in Sichuan, China].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Mar 2013
Zhang Meng-Yan, Liao Hong-Yue, Fan Xue-Jia, Lu Lei, Pei Xiao-Fang, Xu Xin
Abstract excerpt
OBJECTIVE: To investigate the variation of cytotoxic T-lymphocyte (CTL) and neutralizing epitopes in F protein of respiratory syncytial virus (RSV) isolated in Sichuan. METHODS: Nearly full-length of F protein gene of 10 strains of RSV isolated in Sichuan was amplified by RT-PCR and sequenced. The genetic variations, especially the CTL and neutralizing antibody epitopes within different subtypes and genotypes...
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