Article
Acquired resistance to targeted therapies in advanced non-small cell lung cancer: new strategies and new agents.
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting - 1 Jan 2013
West Howard, Oxnard Geoffrey R, Doebele Robert C
Abstract excerpt
Although the transition to molecularly defined patient subgroups in advanced non-small cell lung cancer (NSCLC) often leads to dramatic and prolonged responses to an inhibitor of an identified oncogenic mutation, acquired resistance eventually ensues. The optimal approach to management in that setting remains the subject of ongoing research, although it is possible to identify several points that distinguish it...
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