Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NCL disease mechanisms.

Biochimica et biophysica acta - 1 Nov 2013

Palmer David N, Barry Lucy A, Tyynelä Jaana, Cooper Jonathan D

Abstract excerpt

Despite the identification of a large number of disease-causing genes in recent years, it is still unclear what disease mechanisms operate in the neuronal ceroid lipofuscinoses (NCLs, Batten disease). As a group they are defined by the specific accumulation of protein, either subunit c of mitochondrial ATP synthase or SAPs A and D in lysosome-derived organelles, and regionally specific neurodegeneration. Evidence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to NCL gene
Share to Genetic Predisposition to Disease
Share to Lysosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Mutation

Share to Neuronal Ceroid-Lipofuscinoses

Share to Phenotype

Source

Identifiers

PMID: 23707513
DOI: 10.1016/j.bbadis.2013.05.014

Genes

NCL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NCL disease mechanisms.PMID 23707513Read ↗

Pathomechanisms in the neuronal ceroid lipofuscinoses.Semantic proximity Read ↗

Autophagy in the Neuronal Ceroid Lipofuscinoses (Batten Disease)Semantic proximity Read ↗

Batten disease: clinical aspects, molecular mechanisms, translational science, and future directions.Semantic proximity Read ↗

The neuronal ceroid lipofuscinoses: the same, but different?Semantic proximity Read ↗

Comparative biology of the neuronal ceroid-lipofuscinoses (NCL): an overview.Semantic proximity Read ↗

Progress towards understanding the neurobiology of Batten disease or neuronal ceroid lipofuscinosisSemantic proximity Read ↗

Progress towards understanding the neurobiology of Batten disease or neuronal ceroid lipofuscinosis.Semantic proximity Read ↗

Emerging new roles of the lysosome and neuronal ceroid lipofuscinosesSemantic proximity Read ↗

Neurodegenerative disease: the neuronal ceroid lipofuscinoses (Batten disease).Semantic proximity Read ↗

The neuronal ceroid-lipofuscinoses: from past to present.Semantic proximity Read ↗

Selectivity and Types of Cell Death in the Neuronal Ceroid Lipofuscinoses (NCLs)Semantic proximity Read ↗

The neuronal ceroid-lipofuscinoses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.