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Article

A mutational analysis of the active site loop residues in cis-3-Chloroacrylic acid dehalogenase.

Biochemistry - 18 Jun 2013

Schroeder Gottfried K, Huddleston Jamison P, Johnson William H, Whitman Christian P

Abstract excerpt

cis-3-Chloroacrylic acid dehalogenase (cis-CaaD) from Pseudomonas pavonaceae 170 and a homologue from Corynebacterium glutamicum designated Cg10062 are 34% identical in sequence (54% similar). The former catalyzes a key step in a bacterial catabolic pathway for the nematocide 1,3-dichloropropene, whereas the latter has no known biological activity. Although Cg10062 has the six active site residues (Pro-1, His-28,...

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PMID: 23692140
DOI: 10.1021/bi4004414
PMCID: PMC3718188

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Source receipt: pubmed, retrieved 7 Sept 2026.

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