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Article

Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis.

Frontiers of medicine - 1 Sept 2017

Liu Jian, Wang Weiming

Abstract excerpt

Nephrotic syndrome (NS) is one of the most common glomerular diseases with signs of nephrosis, heavy proteinuria, hypoalbuminemia, and edema. Dysfunction of glomerular filtration barrier causes protein loss through the kidneys. Focal segmental glomerulosclerosis (FSGS) accounts for nearly 20% of NS among children and adults. Adult-onset FSGS/NS is often associated with low response to steroid treatment and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28776307
DOI: 10.1007/s11684-017-0564-1

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