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Article

Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila

1 Jan 2013

Abstract excerpt

Autophagy is a highly conserved degradative pathway that has rapidly emerged as a critical component of immunity and host defense. Studies have implicated autophagy genes in restricting the replication of a diverse array of pathogens, including bacteria, viruses and protozoans. However, in most cases, the in vivo role of antimicrobial autophagy against pathogens has been undefined. Drosophila provides a...

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PMID: 23689401
DOI: 10.1159/000350326

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