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Article

FLT3 inhibitor-induced neutrophilic dermatosis.

Blood - 11 Jul 2013

Fathi Amir T, Le Long, Hasserjian Robert P, Sadrzadeh Hossein, Levis Mark, Chen Yi-Bin

Abstract excerpt

The FLT3-ITD mutation is associated with poor outcomes in acute myeloid leukemia. Multiple FMS-like tyrosine kinase 3 (FLT3)-inhibitors have been studied in clinical trials. Recently, potent FLT3 inhibition was shown to induce terminal differentiation of FLT3-mutant myeloblasts. In 3 patients who developed characteristic skin nodules on initiation of FLT3-inhibition, we conducted dermatopathologic evaluation of...

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Source

Identifiers

PMID: 23687091
DOI: 10.1182/blood-2013-01-478172

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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