Article
Myeloproliferative neoplasms.
Clinical medicine (London, England) - 1 Apr 2013
Publicover Amy, Medd Patrick
Abstract excerpt
The myeloproliferative neoplasms that are associated with the JAK2 mutation are a heterogeneous group of disorders. The additional mutations that result in the clinical phenotype are still the subject of research. As more than one mutation is involved, and as JAK2 has a necessary physiological role (unlike BCR-ABL), the development of targeted therapy remains a challenge. Although new drugs are being developed,...
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