Article
Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio.
International journal of obesity (2005) - 1 Jan 2014
Schleinitz D, Klöting N, Lindgren C M, Breitfeld J, Dietrich A, Schön M R, Lohmann T, Dreßler M, Stumvoll M, McCarthy M I, Blüher M, Kovacs P
Abstract excerpt
OBJECTIVE: We hypothesized that genes within recently identified loci associated with waist-hip ratio (WHR) exhibit fat depot-specific mRNA expression, which correlates with obesity-related traits. METHODS: Adipose tissue (AT) mRNA expression of 6 genes (TBX15/WARS2, STAB1, PIGC, ZNRF3 and GRB14) within these loci showing coincident cis-expression quantitative trait loci was measured in 222 paired samples of...
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