Article
RaoN, a small RNA encoded within Salmonella pathogenicity island-11, confers resistance to macrophage-induced stress.
Microbiology (Reading, England) - 1 Jul 2013
Lee Yong Heon, Kim Sinyeon, Helmann John D, Kim Bae-Hoon, Park Yong Keun
Abstract excerpt
Bacterial small non-coding RNAs act as important regulators that control numerous cellular processes. Here we identified RaoN, a novel small RNA encoded in the cspH-envE intergenic region on Salmonella pathogenicity island-11 (SPI-11). RaoN contributes to survival under conditions of acid and oxidative stress combined with nutrient limitation, which partially mimic the intramacrophage environment. Indeed,...
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