Dual modes of rabies P-protein association with microtubules: a novel strategy to suppress the antiviral response

Abstract excerpt

Conventional nuclear import is independent of the cytoskeleton, but recent data have shown that the import of specific proteins can be either facilitated or inhibited by microtubules (MTs). Nuclear import of the P-protein from rabies virus involves a MT-facilitated mechanism, but here, we show that P-protein is unique in that it also undergoes MT-inhibited import, with the mode of MT-interaction being regulated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Rabies epidemiology and control
• Share to Toxoplasma gondii Research Studies
• Share to Viral Infections and Vectors