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Article

Severe Cenani-Lenz syndrome caused by loss of LRP4 function.

American journal of medical genetics. Part A - 1 Jun 2013

Kariminejad Ariana, Stollfuß Barbara, Li Yun, Bögershausen Nina, Boss Karin, Hennekam Raoul C M, Wollnik Bernd

Abstract excerpt

Limb patterning and growth are complex embryonic processes in which the elaborately orchestrated interplay of diverse endocrine and paracrine factors is crucial to limb integrity. LRP4 is a lipoprotein receptor known for its regulatory effects on LRP5- and LRP6-mediated Wnt signaling, a pathway t...

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Source

Identifiers

PMID: 23636941
DOI: 10.1002/ajmg.a.35920

Genes

LRP4
LRP5
LRP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-23636941-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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