Article
Sox9 and programming of liver and pancreatic progenitors.
The Journal of clinical investigation - 1 May 2013
Kawaguchi Yoshiya
Abstract excerpt
Recent advances in developmental biology have greatly expanded our understanding of progenitor cell programming and the fundamental roles that Sox9 plays in liver and pancreas organogenesis. In the last 2 years, several studies have dissected the behavior of the Sox9+ duct cells in adult organs, but conflicting results have left unanswered the long-standing question of whether physiologically functioning...
Topics
- Alleles
- Animals
- Cell Lineage
- Developmental Biology
- Gene Expression Regulation, Developmental
- Humans
- Integrases
- Liver
- Liver Regeneration
- Mice
- Pancreas
- SOX9 Transcription Factor
