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Article

Age‐related changes in the composition of the cornified envelope in human skin

15 Mar 2013

Abstract excerpt

The main function of the epidermis is to protect us against a multitude of hostile attacks from the environment. Its main cell type, the keratinocytes have a sophisticated system of different proteins and lipids available to form the cornified envelope, which is responsible for the barrier function of the skin. During ageing, dramatic changes are taking place. Some proteins of the SPRR-, S100- and LCE3-family are...

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PMID: 23614739
DOI: 10.1111/exd.12135

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