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Article

EGFP tags affect cellular localization of ATP7B mutants.

CNS neuroscience & therapeutics - 1 May 2013

Zhu Min, Ni Wang, Dong Yi, Wu Zhi-Ying

Abstract excerpt

AIMS: Wilson's disease is an autosomal recessive disorder of copper metabolism due to mutations within ATP7B gene. Clinical investigations indicate that ATP7B truncations are associated with an early age of onset when compared to its missense mutations. In vitro studies show that mislocalization of ATP7B mutants is involved in disease-causing mechanisms. Enhanced green fluorescent protein (EGFP) tags are commonly...

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Identifiers

PMID: 23607698
DOI: 10.1111/cns.12091
PMCID: PMC6493502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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