Article
JAK2 V617F allele burden quantified by real time quantitative polymerase chain reaction and competitive polymerase chain reaction in patients with chronic myeloproliferative neoplasia.
Leukemia & lymphoma - 1 Jan 2014
Kaeda Jaspal, Bonamino Martin, Ayres-Silva Jackline, Solza Cristiana, Ringel Frauke, Blau Olga, Daumas Ademo, Oberender Christian, Dörken Bernd, le Coutre Philipp, Zalcberg Ilana
Abstract excerpt
Assessing the clinical significance of JAK2 V617F mutant allele burden is complicated by a myriad of techniques reported to detect and quantify the mutation. As a consequence, the level of sensitivity and how the data is reported vary. Harmonization of well-defined molecular studies would permit...
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