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Article

Amino acid substitution in the Cυ3 domain causes either elevation or reduction of IgY uptake into egg yolks of quail.

Veterinary immunology and immunopathology - 15 Jun 2013

Takimoto Takuou, Doi Kasumi, Kobayashi Misato, Horio Fumihiko, Murai Atsushi

Abstract excerpt

Egg yolks of avian species contain large quantities of immunoglobulin (Ig) Ys transferred from maternal blood circulation. However, it is unclear how maternal IgYs are incorporated into the egg yolks of maturing oocytes. The aim of this study was to identify the amino acid residues required for efficient IgY transport into the egg yolks of quail by utilizing recombinant quail IgY-Fc (qIgY-Fc). Five amino acid...

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PMID: 23601840
DOI: 10.1016/j.vetimm.2013.03.011

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