Article
Association of COL1A1 polymorphism in Turkish patients with otosclerosis.
American journal of otolaryngology - 1 Jan 2000
Ertugay Omer Cagatay, Ata Pinar, Kalaycik Ertugay Cigdem, Kaya Kerem Sami, Tatlipinar Arzu, Kulekci Semra
Abstract excerpt
OBJECTIVE: To evaluate the role of COL1A1 gene polymorphism in the etiology of otosclerosis. MATERIAL AND METHODS: Peripheric blood samples are obtained from 28 patients diagnosed with otosclerosis and 50 control subjects. DNA's of all samples are isolated and amplified by using the PCR technique. The products are restricted by appropriate enzymes and the allele distributions were compared. RESULTS: SS...
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