Article
BDNF deregulation in Rett syndrome.
Neuropharmacology - 1 Jan 2014
Li Wei, Pozzo-Miller Lucas
Abstract excerpt
BDNF is the best-characterized neurotrophin in terms of its gene structure and modulation, secretion processing, and signaling cascades following its release. In addition to diverse features at the genetic and molecular levels, the abundant expression in several regions of the central nervous system has implicated BDNF as a potent modulator in many aspects of neuronal development, as well as synaptic transmission...
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