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Article

Prevalence of high DNA fragmentation index in male partners of unexplained infertile couples

14 Dec 2012

Abstract excerpt

The sperm chromatin structure assay (SCSA) parameter DNA fragmentation Index (DFI) is a valuable tool for prediction of fertility in vivo. Clinical data show that a DFI above 30% is associated with very low chance for achieving pregnancy by natural conception or by insemination. Already when DFI is above 20% the chance of natural pregnancy is reduced, this despite normal conventional semen parameters. The aim of...

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PMID: 23596042
DOI: 10.1111/j.2047-2927.2012.00041.x

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