Article
Genomic sequence and virulence of clonal isolates of vaccinia virus Tiantan, the Chinese smallpox vaccine strain.
PloS one - 1 Jan 2013
Zhang Qicheng, Tian Meijuan, Feng Yi, Zhao Kai, Xu Jing, Liu Ying, Shao Yiming
Abstract excerpt
Despite the worldwide eradication of smallpox in 1979, the potential bioterrorism threat from variola virus and the ongoing use of vaccinia virus (VACV) as a vector for vaccine development argue for continued research on VACV. In China, the VACV Tiantan strain (TT) was used in the smallpox eradication campaign. Its progeny strain is currently being used to develop a human immunodeficiency virus (HIV) vaccine....
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