Characterization of miRNA Expression in Human Degenerative Lumbar Disks

Abstract excerpt

BACKGROUND DATA: microRNAs (miRNAs) are short ∼22 nucleotide RNA sequences that regulate messengerRNA translation. miRNAs have shown to play a role in synthesis of inflammatory mediators. Since inflammation play a role in intervertebral disk (IVD) degeneration, the objective was to isolate miRNA from human lumbar intervertebral disks and subsequently characterize the difference in miRNA expression between the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cervical and Thoracic Myelopathy
• Share to Osteoarthritis Treatment and Mechanisms
• Share to Spine and Intervertebral Disc Pathology