Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kruppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma

12 Apr 2013

Abstract excerpt

Krüppel-like factor 4 is a transcription factor with anti-proliferative effects in differentiated cells, but with the ability to reprogram adult cells into cell-cycling pluripotent cells. In cancer, Krüppel-like factor 4 acts as either an anti-oncogene or an oncogene. We analyzed Krüppel-like factor 4 gene expression in multiple myeloma using Affymetrix microarrays. We generated conditionally expressing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Myeloid Leukemia Treatments
Share to Epigenetics and DNA Methylation
Share to Kruppel-like factors research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23585530
DOI: 10.3324/haematol.2012.066944

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Kruppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myelomaPMID 23585530Read ↗

Transcriptional Profiling of Krüppel-like Factor 4 Reveals a Function in Cell Cycle Regulation and Epithelial DifferentiationSemantic proximity Read ↗

POZ Domain Transcription Factor Kaiso is a Downstream Effector of STAT1 for Multiple Myeloma Cell Survival and is also essential for Anoikis Resistance of Metastatic Solid TumorsSemantic proximity Read ↗

Restoration of microRNA-214 expression reduces growth of myeloma cells through positive regulation of P53 and inhibition of DNA replicationSemantic proximity Read ↗

Targeting the GCK pathway: a novel and selective therapeutic strategy against RAS-mutated multiple myeloma.Semantic proximity Read ↗

Krüppel-like factor 4 exhibits antiapoptotic activity following γ-radiation-induced DNA damageSemantic proximity Read ↗

Emerging roles of Kruppel-like factor 6 and Kruppel-like factor 6 splice variant 1 in ovarian cancer progression and treatment.Semantic proximity Read ↗

RARα2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myelomaSemantic proximity Read ↗

Role for Krüppel-Like Factor 4 in Determining the Outcome of p53 Response to DNA DamageSemantic proximity Read ↗

Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myelomaSemantic proximity Read ↗

Krüppel-like factor 5 mediates the transforming activity of oncogenic H-RasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.