Article
Blood-brain barrier destruction determines Fisher/Bickerstaff clinical phenotypes: an in vitro study.
Journal of neurology, neurosurgery, and psychiatry - 1 Jul 2013
Saito Kazuyuki, Shimizu Fumitaka, Koga Michiaki, Sano Yasuteru, Tasaki Ayako, Abe Masaaki, Haruki Hiroyo, Maeda Toshihiko, Suzuki Seiko, Kusunoki Susumu, Mizusawa Hidehiro, Kanda Takashi
Abstract excerpt
OBJECTIVE: To ascertain the hypothesis that the phenotypic differences between Bickerstaff's brainstem encephalitis (BBE) and Miller Fisher syndrome (MFS) are derived from the differences in the effects of sera on blood-brain barrier (BBB) and blood-nerve barrier. BACKGROUND: Antibodies against GQ1b are frequently detected in BBE and MFS, and these two disorders may share the same pathogenesis, but the clinical...
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