Article
Description of two new HLA-C alleles: C*08:63 and C*14:44.
International journal of immunogenetics - 1 Feb 2014
Mantovani M, Longhi E, Frison S, Lazzari R, Espadas De Arias A, Piccolo G, Poli F
Abstract excerpt
Here, we present two new HLA allelic variants at C locus: HLA-C*08:63 and HLA-C*14:44 detected by sequence-based typing. In both cases, a single-nucleotide mutation in exon 3 is responsible for a change in aminoacid translation. The extremely high polymorphism of human leucocyte antigen (HLA) system in human genome is responsible for the capability to recognize different antigens, including non-self-MHC (Major...
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