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Looking for more reliable biomarkers in breast cancer: Comparison between routine methods and RT-qPCR

23 Sept 2021

Abstract excerpt

PURPOSE: Decades of quality control efforts have raised the standards of immunohistochemistry (IHC), the principle method used for biomarker testing in breast cancer; however, computational pathology and reverse transcription quantitative PCR (RT-qPCR) may also hold promise for additional substantial improvements. METHODS: Herein, we investigated discrepancies in the assessment of estrogen receptor (ER),...

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PMID: 34555047
DOI: 10.1371/journal.pone.0255580

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