Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I.

European journal of heart failure - 1 Sept 2013

Hollingsworth Kieren G, Willis Tracey A, Bates Matthew G D, Dixon Ben J, Lochmüller Hanns, Bushby Kate, Bourke John, MacGowan Guy A, Straub Volker

Abstract excerpt

AIM: The mechanisms of cardiac dysfunction in limb girdle muscular dystrophy 2I (LGMD2I) are unclear. This study assessed deficits in cardiac morphology, function, and metabolism quantitatively in patients with a confirmed genetic diagnosis of the homozygous c.826C > A FKRP (fukutin-related protein) mutation, using a comprehensive magnetic resonance (MR) examination. METHODS AND RESULTS: Ten patients (7 male and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Magnetic Resonance Imaging, Cine
Share to Muscular Dystrophies, Limb-Girdle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pentosyltransferases

Share to Pericardium

Share to Spectrum Analysis

Share to Stroke Volume

Share to Systole

Share to Ventricular Dysfunction, Left

Source

Identifiers

PMID: 23576288
DOI: 10.1093/eurjhf/hft057

Genes

FKRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I.PMID 23576288Read ↗

Cardiovascular magnetic resonance of cardiomyopathy in limb girdle muscular dystrophy 2B and 2I.Semantic proximity Read ↗

Cardiac assessment of limb-girdle muscular dystrophy 2I patients: an echography, Holter ECG and magnetic resonance imaging study.Semantic proximity Read ↗

Sexually dimorphic skeletal muscle and cardiac dysfunction in a mouse model of limb girdle muscular dystrophy 2i.Semantic proximity Read ↗

Cardiac and respiratory failure in limb-girdle muscular dystrophy 2I.Semantic proximity Read ↗

Increased left ventricular torsion in hypertrophic cardiomyopathy mutation carriers with normal wall thickness.Semantic proximity Read ↗

Cardiomyopathy in limb girdle muscular dystrophy R9, FKRP related.Semantic proximity Read ↗

Characteristic cardiac phenotypes are detected by cardiovascular magnetic resonance in patients with different clinical phenotypes and genotypes of mitochondrial myopathy.Semantic proximity Read ↗

Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers†Semantic proximity Read ↗

Cardiac Involvement in Patients With Limb-Girdle Muscular Dystrophy Type 2 and Becker Muscular DystrophySemantic proximity Read ↗

Association between specific dystrophin gene mutations and myocardial fibrosis by cardiovascular magnetic resonance imaging in patients with Duchenne and Becker muscular dystrophySemantic proximity Read ↗

Comparative analysis of right ventricular strain in Fabry cardiomyopathy and sarcomeric hypertrophic cardiomyopathySemantic proximity Read ↗

Cardiac pathology exceeds skeletal muscle pathology in two cases of limb‐girdle muscular dystrophy type 2ISemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.