Article
Increased left ventricular torsion in hypertrophic cardiomyopathy mutation carriers with normal wall thickness.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance - 10 Jan 2011
Rüssel Iris K, Brouwer Wessel P, Germans Tjeerd, Knaapen Paul, Marcus J Tim, van der Velden Jolanda, Götte Marco J W, van Rossum Albert C
Abstract excerpt
BACKGROUND: Increased left ventricular (LV) torsion has been observed in patients with manifest familial hypertrophic cardiomyopathy (HCM), and is thought to be caused by subendocardial dysfunction. We hypothesize that increased LV torsion is already present in healthy mutation carriers with normal wall thickness. METHODS: Seventeen carriers with an LV wall thickness <10 mm, and seventeen age and gender matched...
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