Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between ISL1 variants and susceptibility to ventricular septal defect in a Chinese cohort.

Molecular diagnosis & therapy - 1 Apr 2013

Lang Jilu, Tian Weichen, Sun Xian

Abstract excerpt

AIM: It has previously been reported that ISLET1 (ISL1) plays a fundamental role in cardiac morphogenesis. This study investigated the possible association between variants in the ISL LIM homeobox 1 (ISL1) gene and congenital ventricular septal defect (VSD) in a Chinese cohort. METHODS: A total of 512 congenital VSD patients and 612 unrelated age- and sex-matched healthy control subjects were enrolled in this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Case-Control Studies
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Septal Defects, Ventricular

Share to Infant

Share to LIM-Homeodomain Proteins

Share to Transcription Factors

Share to Young Adult

Source

Identifiers

PMID: 23572340
DOI: 10.1007/s40291-013-0033-8

Genes

ISL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between ISL1 variants and susceptibility to ventricular septal defect in a Chinese cohort.PMID 23572340Read ↗

Genetic studies in the Pakistani population reveal novel associations with ventricular septal defects (VSDs).Semantic proximity Read ↗

Study of variants associated with ventricular septal defects (VSDs) highlights the unique genetic structure of the Pakistani population.Semantic proximity Read ↗

Correlations between ISL1 rs1017 polymorphism and congenital heart disease risk: A PRISMA-compliant meta-analysis.Semantic proximity Read ↗

Genetic variations of ISL1 associated with human congenital heart disease in Chinese Han people.Semantic proximity Read ↗

Identification of variants of ISL1 gene promoter and cellular functions in isolated ventricular septal defects.Semantic proximity Read ↗

First report of polymorphisms in MTRR, GATA4, VEGF, and ISL1 genes in Pakistani children with isolated ventricular septal defects (VSD).Semantic proximity Read ↗

Common variation in ISL1 confers genetic susceptibility for human congenital heart disease.Semantic proximity Read ↗

FLT4 gene polymorphisms influence isolated ventricular septal defect predisposition in a Southwest China population.Semantic proximity Read ↗

[Association between two SNPs of ISL1 gene and congenital heart disease in children].Semantic proximity Read ↗

Molecular mechanisms of Ellis‑van Creveld gene variations in ventricular septal defect.Semantic proximity Read ↗

FLT4 gene polymorphisms influence isolated ventricular septal defects predisposition in a Southwest China populationSemantic proximity Read ↗

ISL1 common variant rs1017 is not associated with susceptibility to congenital heart disease in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.