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Article

Rab proteins and Rab-associated proteins: major actors in the mechanism of protein-trafficking disorders

7 May 2008

Abstract excerpt

UNLABELLED: Ras-associated binding (Rab) proteins and Rab-associated proteins are key regulators of vesicle transport, which is essential for the delivery of proteins to specific intracellular locations. More than 60 human Rab proteins have been identified, and their function has been shown to depend on their interaction with different Rab-associated proteins regulating Rab activation, post-translational...

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PMID: 18463892
DOI: 10.1007/s00431-008-0740-z

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