Article
Pathway of glycine betaine biosynthesis in Aspergillus fumigatus.
Eukaryotic cell - 1 Jun 2013
Lambou Karine, Pennati Andrea, Valsecchi Isabel, Tada Rui, Sherman Stephen, Sato Hajime, Beau Remi, Gadda Giovanni, Latgé Jean-Paul
Abstract excerpt
The choline oxidase (CHOA) and betaine aldehyde dehydrogenase (BADH) genes identified in Aspergillus fumigatus are present as a cluster specific for fungal genomes. Biochemical and molecular analyses of this cluster showed that it has very specific biochemical and functional features that make it unique and different from its plant and bacterial homologs. A. fumigatus ChoAp catalyzed the oxidation of choline to...
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