Article
Gene regulation by CcpA and catabolite repression explored by RNA-Seq in Streptococcus mutans.
PloS one - 1 Jan 2013
Zeng Lin, Choi Sang Chul, Danko Charles G, Siepel Adam, Stanhope Michael J, Burne Robert A
Abstract excerpt
A bacterial transcriptome of the primary etiological agent of human dental caries, Streptococcus mutans, is described here using deep RNA sequencing. Differential expression profiles of the transcriptome in the context of carbohydrate source, and of the presence or absence of the catabolite control protein CcpA, revealed good agreement with previously-published DNA microarrays. In addition, RNA-seq considerably...
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