Article
BRCA mutations cause reduction in miR-200c expression in triple negative breast cancer.
Gene - 10 Feb 2015
Erturk Elif, Cecener Gulsah, Tezcan Gulcin, Egeli Unal, Tunca Berrin, Gokgoz Sehsuvar, Tolunay Sahsine, Tasdelen Ismet
Abstract excerpt
Triple negative breast cancer (TNBC) is the most aggressive and poorly understood subclass of breast cancer (BC). Over the recent years, miRNA expression studies have been providing certain detailed overview that aberrant expression of miRNAs is associated with TNBC. Although TNBC tumors are strongly connected with loss of function of BRCA genes, there is no knowledge about the effect of BRCA mutation status on...
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