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Article

The expression of BRCA1, P53, KAI1, and Nm23 in ovaries of BRCA1 mutation carriers after prophylactic adnexectomy.

Archives of gynecology and obstetrics - 1 Oct 2013

Markowska J, Bar J, Mądry R, Słomska I, Mardas M, Grabowski J P

Abstract excerpt

INTRODUCTION: High mortality rate, absence of reliable methods for early diagnosis and poor prognosis of advanced ovarian cancer prompted to investigate the role of prophylactic oophorectomy in BRCA1 mutation carriers as well as evaluate the expression of BRCA1, p53, Nm23, and KAI1 proteins in ovarian tissue from these patients. MATERIALS AND METHODS: Ovaries from BRCA1 mutation carriers underwent prophylactic...

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Share to BRCA1 Protein
Share to Genes, BRCA1
Share to Hereditary Breast and Ovarian Cancer Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to NM23 Nucleoside Diphosphate Kinases

Share to Ovariectomy

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Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 23553196
DOI: 10.1007/s00404-013-2825-9
PMCID: PMC3778227

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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