Article
[Distributions of polymorphisms of genes of some components of hemostasis in patients with ischemic heart disease].
Kardiologiia - 1 Jan 2009
Pavlova T V, Poliakov V P, Dupliakov D V, Khokhlunov S M, Kirillov V I, Shavkunov S A
Abstract excerpt
We have studied structure of polymorphisms of genes of blood clotting factors II, V, VII, platelet membrane glycoprotein IIIa (GPIIIa) and enzyme methylenetetrahydrofolate reductase (MTHFR) in patients with ischemic heart disease (IHD). In this cohort of patients most prevalent are polymorphism PLAA1/A2 of GPIIIa gene and 677T/T polymorphism of MTHFR gene. Inconsistency of existing evidence on effect of R/Q...
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