Article
[Molecular pathogenesis of primary cardiomyopathy and calcium sensitivity].
Clinical calcium - 1 Apr 2013
Kimura Akinori
Abstract excerpt
Idiopathic cardiomyopathy (ICM) is defined as the cardiac disease caused by functional abnormality of cardiomyocytes, which can be classified into several clinical phenotypes such as hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) . Familial occurrence is well recognized for ICM, and genetic analyses have revealed that mutations in genes for components of contractile elements, Z-disc, I band...
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