Article
A conserved spiral structure for highly diverged phage tail assembly chaperones.
Journal of molecular biology - 24 Jul 2013
Pell Lisa G, Cumby Nichole, Clark Teresa E, Tuite Ashleigh, Battaile Kevin P, Edwards Aled M, Chirgadze Nickolay Y, Davidson Alan R, Maxwell Karen L
Abstract excerpt
Tail assembly chaperones (TACs) are a family of proteins likely required for the morphogenesis of all long-tailed phages. In this study, we determined the crystal structure of gp13, the TAC of phage HK97. This structure is similar to that of the TAC from the Lactococcus phage p2 and two unannotated structures of likely TACs encoded in prophage-derived regions of Bacillus subtilis and Bacillus stearothermophilus....
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