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Article

Genomics of Loa loa, a Wolbachia-free filarial parasite of humans

24 Mar 2013

Abstract excerpt

Thomas Nutman and colleagues report the draft genome of the filarial pathogen Loa loa, the African eyeworm. They also report coverage of two other filarial pathogens, Wuchereria bancrofti and Onchocerca volvulus. Unlike most filariae, L. loa lacks an obligate intracellular Wolbachia endosymbiont, and comparative genomic analyses suggest that the L. loa genome does not contain new metabolic synthesis or transport...

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PMID: 23525074
DOI: 10.1038/ng.2585

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