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Article

New fluoroquinolones active against fluoroquinolones-resistant Mycobacterium tuberculosis strains.

Tuberculosis (Edinburgh, Scotland) - 1 Jul 2013

Guerrini Valentina, De Rosa Maria, Pasquini Serena, Mugnaini Claudia, Brizzi Antonella, Cuppone Anna Maria, Pozzi Gianni, Corelli Federico

Abstract excerpt

A set of 21 new fluoroquinolones bearing an aromatic or heteroaromatic moiety at C-7 and an alkyl group at N-1 were synthesized based on the lead structure of pirfloxacin and tested in vitro against Mycobacterium tuberculosis (M. tuberculosis) H37Rv by MIC determination in liquid medium. Among th...

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Source

Identifiers

PMID: 23523640
DOI: 10.1016/j.tube.2013.02.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23523640-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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