Article
Familial clustering and genetic heterogeneity in Meniere's disease.
Clinical genetics - 1 Mar 2014
Requena T, Espinosa-Sanchez J M, Cabrera S, Trinidad G, Soto-Varela A, Santos-Perez S, Teggi R, Perez P, Batuecas-Caletrio A, Fraile J, Aran I, Martin E, Benitez J, Pérez-Fernández N, Lopez-Escamez J A
Abstract excerpt
The aims of this study were to estimate the prevalence of familial cases in patients with Meniere's disease (MD) and to identify clinical differences between sporadic and familial MD. We recruited 1375 patients with definite MD according to the American Academy of Otolaryngology-Head and Neck Surgery criteria, obtaining the familial history of hearing loss or episodic vertigo by direct interview or a postal...
Topics
- Adult
- Age of Onset
- Aged
- Cohort Studies
- Family
- Female
- Genetic Heterogeneity
- Genetic Predisposition to Disease
- Humans
- Italy
- Male
- Meniere Disease
- Middle Aged
- Pedigree