Article
Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol.
Phytomedicine : international journal of phytotherapy and phytopharmacology - 15 Apr 2013
Kuete Victor, Tchakam Patricia D, Wiench Benjamin, Ngameni Bathelemy, Wabo Hippolyte K, Tala Michel F, Moungang Marlyse L, Ngadjui Bonaventure T, Murayama Tetsuya, Efferth Thomas
Abstract excerpt
INTRODUCTION: The emergence of drug-resistant cancer cells drastically reduces the efficacy of many antineoplasic agents and, consequently, increases the frequency of therapeutic failure. Benzophenones are known to display many pharmacological properties including cytotoxic activities. The present study was aimed at investigating the cytotoxicity and the modes of action of four naturally occurring benzophenones...
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