Article
Is junk DNA bunk? A critique of ENCODE.
Proceedings of the National Academy of Sciences of the United States of America - 2 Apr 2013
Doolittle W Ford
Abstract excerpt
Do data from the Encyclopedia Of DNA Elements (ENCODE) project render the notion of junk DNA obsolete? Here, I review older arguments for junk grounded in the C-value paradox and propose a thought experiment to challenge ENCODE's ontology. Specifically, what would we expect for the number of functional elements (as ENCODE defines them) in genomes much larger than our own genome? If the number were to stay more or...
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