Article
Impact of JAK2 V617F mutation on hemogram variation in patients with non-reactive elevated platelet counts.
PloS one - 1 Jan 2013
Zhou Juan, Ye Yuanxin, Zeng Shugen, Zhou Yi, Mao Zhigang, Song Xingbo, Ying Binwu, Lu Xiaojun, Jiang Hong, Wang Lanlan
Abstract excerpt
BACKGROUND: Non-reactive platelet counts elevation occurs mainly in myeloproliferative disorders (MPDs), which have been reported to be closely associated with JAK2 V617F mutation. Complete blood cell count (CBC) is essential in diagnosis of MPDs, however, the impact of JAK2 V617F mutation on the patients' hemogram variation remains not clear. METHODS: JAK2 V617F mutation was detected by allele specific real-time...
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