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Article

Mouse models of human INAD by Pla2g6 deficiency.

Histology and histopathology - 1 Aug 2013

Wada Haruka, Kojo Satoshi, Seino Ken-ichiro

Abstract excerpt

Infantile neuroaxonal dystrophy (INAD) is a severe neurodegenerative disease characterized by its early onset. PLA2G6, which encodes a phospholipase A2, iPLA₂β, has been identified as a causative gene of INAD. iPLA₂β has been shown to be involved in various physiological and pathological processes, including immunity, cell death, and cell membrane homeostasis. Gene targeted mice with a null mutation of Pla2g6...

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Source

Identifiers

PMID: 23467909
DOI: 10.14670/HH-28.965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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