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Article

Development of a specific method to evaluate 8-hydroxy,2-deoxyguanosine in sperm nuclei: relationship with semen quality in a cohort of 94 subjects

1 Mar 2013

Abstract excerpt

Oxidative stress (OS) is involved in many disoders including male infertility. Human spermatozoa are very sensitive targets of reactive oxygen species (ROS) and most sperm functions are impaired in the case of OS. In addition unbalanced production of ROS is considered one of the most important causes of sperm DNA fragmentation, a semen trait of infertile men. The relationship between oxidative damage and semen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23457372
DOI: 10.1530/rep-12-0404

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