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Article

Hemimegalencephaly, a paradigm for somatic postzygotic neurodevelopmental disorders

28 Feb 2013

Abstract excerpt

PURPOSE OF REVIEW: Combining human genomics and molecular biology, recent studies have made pivotal progress toward understanding the cause of hemimegalencephaly (HME) and other cerebral megalencephaly syndromes. The present article highlights recent advances of the genetic cause of these conditions, and considers the role of somatic postzygotic genetic lesions in brain maldevelopment. RECENT FINDINGS: Studies...

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PMID: 23449172
DOI: 10.1097/wco.0b013e32835ef373

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